
FinO-RNA interactions.
AHFMR Fellowship (2000-2002)
20 during tenure in Glover's laboratory, 20 total.

Faculty of Medicine and Dentistry 75th Anniversary Award (2011)
I am working on polynucleotide kinase/phosphatase (PNKP) which has an essential role in DNA repair pathways. I am focusing on structural studies of PNKP substrate binding. In addition, I am characterizing inhibitors for PNKP which can be developed into novel cancer drugs that sensitize tumor cells to radio- and chemotherapy.
Faculty of Medicine and Dentistry 75th Anniversary Award (2011)
One during tenure in Glover's laboratory, one total.

AHFMR Studentship (2011-2016)
AHFMR Studentship (2011-2016)
NSERC Alexander Graham Bell Canada Graduate Scholarship (2010)
Five during tenure in Glover's laboratory, six total.

I study proteins involved in bacterial conjugation, a process responsible for diversifying bacterial genomes and quick dissemination of antibiotic resistance. Specifically, we want to understand how a single stranded DNA is processed and transferred in response to an unidentified mating signal generated by intimate donor-recipient cell contact.
AHFMR Fellowship (2006-2007)
CIHR Fellowship (2006-2009)
Leaders in Biochemistry Postdoctoral Fellows Award (2007)
Leaders in Biochemistry Postdoctoral Fellows Award (2010)
Eight during tenure in Glover's laboratory, eight total.

I study the structure and function of the Bmi1-Ring1B polycomb group ubiquitin ligase complex.
Two during tenure in Glover's laboratory, two total.

Queen Elizabeth II Graduate Scholarship - Doctoral Level (2009-2010, 2010-2011)
My work focuses on the polynucleotide kinase/phosphatase (PNKP)/XRCC4/DNA Ligase IV non-homologous end joining (NHEJ) DNA repair complex. This assembly is responsible for processing abnormal DNA end chemistries would otherwise preclude the final repair step of NHEJ in double-strand break repair. I study the structural dynamics and enzymatic activities of this complex.
Queen Elizabeth II Graduate Scholarship - Doctoral Level (2009-2010, 2010-2011)
Graduate Students’ Association Research Communication Outreach Award (2011)
Government of Alberta Graduate Citizenship Award for Student Service (2009)
Biological Sciences Undergraduate Research Award (2006)
Two during tenure in Glover's laboratory, two total.
2010 Alberta Cancer Foundation Research Meeting - Cancer Research in Alberta: From Bench to Society, November 2010, Banff, AB (R. Daniel Aceytuno, Ross A. Edwards, Ryan Au, J.N. Mark Glover): “Structural dynamics and enzymatic studies of the NHEJ XRCC4/DNA Ligase IV/polynucleotide kinase-phosphatase DNA repair complex.”
2010 Alberta Cancer Foundation Research Meeting - Cancer Research in Alberta: From Bench to Society, November 2010, Banff, AB (R. Daniel Aceytuno, Ross A. Edwards, Ryan Au, J.N. Mark Glover): “Structural dynamics and enzymatic studies of the NHEJ XRCC4/DNA Ligase IV/polynucleotide kinase-phosphatase DNA repair complex.”
Alberta Genomic Instability and Aging Conference, June 2010, Calgary, AB (R. Daniel Aceytuno, Ross A. Edwards, Ryan Au, J.N. Mark Glover): “Structural dynamics of the NHEJ XRCC4/DNA Ligase IV/polynucleotide kinase-phosphatase DNA repair complex.”
Ninth Annual Structural Biology of DNA Repair Program Project Workshop, March 2010, Berkeley, CA (R. Daniel Aceytuno, Ross A. Edwards, Ryan Au, J.N. Mark Glover): “Small-angle X-ray scattering models of the NHEJ XRCC4/DNA Ligase IV and XRCC4/DNA Ligase IV/polynucleotide kinase phosphatase DNA repair complexes”
2009 Research Meeting of the Alberta Cancer Research Institute - Celebrating Excellence in Cancer Research in Alberta, November 2009, Banff, AB (R. Daniel Aceytuno, Ross A. Edwards, Ryan Au, J.N. Mark Glover): “Structural studies of the non-homologous end joining XRCC4/DNA Ligase IV/polynucleotide kinase end-processing assembly by small-angle X-ray scattering”
Southern Alberta Cancer Research Institute Genomic Instability and Aging Conference, June 2009, Calgary, AB (R. Daniel Aceytuno, Ryan Au, Nina K. Bernstein, J.N. Mark Glover): “Structural studies of the XRCC4/DNA Ligase IV/polynucleotide kinase end-processing assembly in non-homologous end joining”
3rd US/EU International Conference on Endogenous Genome Damage and Repair, February 2009, Galveston, TX (R. Daniel Aceytuno, Ryan Au, Nina K. Bernstein, J.N. Mark Glover): “Structural studies of the XRCC4/DNA Ligase IV/polynucleotide kinase end-processing assembly in non-homologous end joining”
2nd Annual Alberta Cancer Research Institute Research Meeting - Building Bridges and Closing Gaps: Towards an Integrated Approach to Cancer Research, November 2008, Banff, AB (R. Daniel Aceytuno, Ryan Au, Nina K. Bernstein, J.N. Mark Glover): “Structural studies of the XRCC4/DNA Ligase IV/polynucleotide kinase end-processing assembly in non-homologous end joining”

Mammalian Polynucleotide Kinase/Phosphatase (PNKP) is a key enzyme in the repair of DNA strand breaks. We have elucidated the structure and minimal substrate preferences of PNKP. We are working toward a detailed structural understanding of how PNKP interacts with its substrates with the aim of applying this knowledge to inhibitor design.
NCIC Fellowship (2002-2004)
NCIC Terry Fox Fellowship
Seven during tenure in Glover's laboratory, seven total.

I am trying to acquire the structures of replicative stress response proteins by crystallography, and characterize them biochemically.
One during tenure in Glover's laboratory, one total.

Faculty of Medicine and Dentistry 75th Anniversary Award (2010)
I study different aspects of the DNA damage response, including homologous recombination and cell growth regulation. Current research includes screening and characterization of potential small molecule inhibitors of BRCA1 that may prove to be useful therapeutically, as well as structural studies of K63 E3 ubiquitin ligases involved in checkpoint control, such as CHFR.
Faculty of Medicine and Dentistry 75th Anniversary Award (2010)
Queen Elizabeth Doctoral Award (2009-2010)
Three during tenure in Glover's laboratory, three total.

Canadian Institutes of Health Research Fellowship (2004-2007)
I am interested in miRNA mediated gene regulation and the role of pri-miRNA tertiary structure in miRNA biogenesis. Approximately 50% of miRNAs are expressed as a pri-miRNA cluster containing 2-8 miRNAs per transcript. I am investigating what role the clustering of miRNAs has on their expression and subsequent gene regulation at the proteome level.
Canadian Institutes of Health Research Fellowship (2004-2007)
Natural Sciences and Engineering Research Council Postdoctoral Fellowship (2002-2004)
Walter C. Sumner Fellowship (2001)
John C. Bunting Graduate Prize in Organic Chemistry (2000)
Ontario Graduate Scholarship (1998-2001)
Seven during tenure in Glover's laboratory, 15 total.

Alberta Heritage Foundation for Medical Research Fellowship (2011-2014)
Aprataxin-like-factor (APLF) is a new member of the Non-Homologous End Joining (NHEJ) DNA repair pathway that interacts with XRCC4 and Ku80. My project focuses on a structural characterization of thoses protein complexes to probe further their role in the NHEJ pathway.
Alberta Heritage Foundation for Medical Research Fellowship (2011-2014)
Six during tenure in Glover's laboratory, eight total.

Six during tenure in Glover's laboratory, six total.

Canada Graduate Scholarships Doctoral Award (2003-2005)
Structural investigations of Ndt80 in complex with DNA: Implications for DNA-protein interactions and transcriptional regulation.
Canada Graduate Scholarships Doctoral Award (2003-2005)
Faculty of Medicine and Dentistry 75th Anniversary Award 2000
AHFMR Studentship (2001-2006)
Three during tenure in Glover's laboratory, three total.

Investigation of the BRCT repeats in human hereditary breast cancer and DNA damage response.
Six during tenure in Glover's laboratory, six total.

Profiling Alberta Graduate Students Award (2010)
I work on the structural biology of TopBP1 in the DNA damage response. I am interested in characterizing protein-protein interactions that are critical for the role of TopBP1 in replication stress response.
Profiling Alberta Graduate Students Award (2010)
Queen Elizabeth Doctoral Award (2008-2009)
CIHR Masters Award (2006-2007)
ACB Graduate Studentship (2006-2007)
Lionel B. Pett Graduate Scholarship in Biochemistry (2005)
Eight during tenure in Glover's laboratory, eight total.

I study the structure and function of the polynucleotide kinase/phosphatase (PNKP)/XRCC1/DNA Ligase III base excision repair (BER) complex.
Vatat Postdoc fellowship, The Sackler Faculty of Medicine, Tel Aviv University, Israel (2010)
Marian Gertner Institute for Medical Nanosystems Postdoc fellowship, The Sackler Faculty of Medicine, Tel Aviv University, Israel (2010)
Scholarship for Excellence, The Sackler Faculty of Medicine, Tel Aviv University, Israel (2003)
One during tenure in Glover's laboratory, six total.

My research is on the F-plasmid regulatory protein, TraJ.
Two during tenure in Glover's laboratory, two total.

Frederick Banting and Charles Best Canada Graduate Scholarship
My project focuses on the biochemical and structural characterization of CpxP, a periplasmic protein that regulates the Cpx envelope stress response system in Gram-negative bacteria such as E. coli.
Frederick Banting and Charles Best Canada Graduate Scholarship
President's Doctoral Prize of Distinction (2010)
AHFMR Studentship (2006-2011)
CIHR Canada Graduate Scholarship Masters Award 2005
Three during tenure in Glover's laboratory, three total.

Structural Studies of the BRCA1 BRCT Domain.
12 during tenure in Glover's laboratory, 12 total.

Frederick Banting and Charles Best Canada Graduate Scholar (2009-2011)
I work on TraM of F-like plasmids, a protein essential for conjugative DNA transfer. My projects are the characterization of TraM interaction with DNA at the plasmid origin of transfer region, and the interaction of TraM with TraD, a protein which is part of the transmembrane complex that mediates DNA transfer.
Frederick Banting and Charles Best Canada Graduate Scholar (2009-2011)
President's Doctoral Prize of Distinction (2010)
Faculty of Medicine and Dentistry - 75th Anniversary Award (2006)
Five during tenure in Glover's laboratory, five total.

AIHS Postdoctoral Fellowship (2013-2016)
Activity of p53, the major human tumor suppressor, is regulated by the serine/threonine phosphatase, PP1. PP1 dephosphorylates p53 via interactions with members of the ASPP (Apoptotic Stimulating Proteins of p53) family. My project focuses on the structural and biochemical characterization of the interactions of PP1/ASPP/p53 complexes, with an ultimate goal to develop novel anti-cancer drug leads.
AIHS Postdoctoral Fellowship (2013-2016)